ADME: Absorption • Distribution • Metabolism • Excretion (Clearance)
Loading dose • Volume of distribution (Initial) • Rate of infusion
Compartment • Bioequivalence • Bioavailability
Onset of action • Biological half-life • Plasma protein binding
Toxicity (Neurotoxicology) • Dose-response relationship (Efficacy, Potency)
Agonist: Inverse agonist • Irreversible agonist • Partial agonist • Superagonist • Physiological agonist
Antagonist: Competitive antagonist • Irreversible antagonist • Physiological antagonist
Drug tolerance: Tachyphylaxis
