Chemical formula

Al2(SO4)3
Example of a chemical formula, aluminium sulfate

A chemical formula or molecular formula is a way of expressing information about the atoms that constitute a particular chemical compound.

The chemical formula identifies each constituent element by its chemical symbol and indicates the number of atoms of each element found in each discrete molecule of that compound. If a molecule contains more than one atom of a particular element, this quantity is indicated using a subscript after the chemical symbol (although 18th-century books often used superscripts) and also can be combined by more chemical elements. For example, methane, a small molecule consisting of one carbon atom and four hydrogen atoms, has the chemical formula CH₄. The sugar molecule glucose has six carbon atoms, twelve hydrogen atoms and six oxygen atoms, so its chemical formula is C₆H₁₂O₆.

Chemical formulas may be used in chemical equations to describe chemical reactions. For ionic compounds and other non-molecular substances an empirical formula may be used, in which the subscripts indicate the ratio of the elements.

The 19th-century Swedish chemist Jöns Jacob Berzelius worked out this system for writing chemical formulas.

Molecular geometry and structural formulas

File:Isobutane-numbered-2D.png

Isobutane
Molecular formula: C₄H₁₀
Semi-structural formula: (CH₃)₃CH

File:Butan Lewis.svg

Butane
Molecular formula: C₄H₁₀
Semi-structural formula: CH₃CH₂CH₂CH₃

The connectivity of a molecule often has a strong influence on its physical and chemical properties and behavior. Two molecules composed of the same numbers of the same types of atoms (i.e. a pair of isomers) might have completely different chemical and/or physical properties if the atoms are connected differently or in different positions. In such cases, a structural formula is useful, as it illustrates which atoms are bonded to which other ones. From the connectivity, it is often possible to deduce the approximate shape of the molecule.

A chemical formula supplies information about the types and spatial arrangement of bonds in the chemical, though it does not necessarily specify the exact isomer. For example ethane consists of two carbon atoms single-bonded to each other, with each carbon atom having three hydrogen atoms bonded to it. Its chemical formula can be rendered as CH₃CH₃. In ethylene there is a double bond between the carbon atoms (and thus each carbon only has two hydrogens), therefore the chemical formula may be written: CH₂CH₂, and the fact that there is a double bond between the carbons is implicit because carbon has a valence of four. However, a more explicit method is to write H₂C=CH₂ or less commonly H₂C::CH₂. The two lines (or two pairs of dots) indicate that a double bond connects the atoms on either side of them.

A triple bond may be expressed with three lines or pairs of dots, and if there may be ambiguity, a single line or pair of dots may be used to indicate a single bond.

Molecules with multiple functional groups that are the same may be expressed by enclosing the repeated group in round brackets. For example isobutane may be written (CH₃)₃CH. This semi-structural formula implies a different connectivity from other molecules that can be formed using the same atoms in the same proportions (isomers). The formula (CH₃)₃CH implies a central carbon atom attached to one hydrogen atom and three CH₃ groups. The same number of atoms of each element (10 hydrogens and 4 carbons, or C₄H₁₀) may be used to make a straight chain molecule, butane: CH₃CH₂CH₂CH₃.

The alkene but-2-ene has two isomers which the chemical formula CH₃CH=CHCH₃ does not identify. The relative position of the two methyl groups must be indicated by additional notation denoting whether the methyl groups are on the same side of the double bond (cis or Z) or on the opposite sides from each other (trans or E).

Polymers

For polymers, parentheses are placed around the repeating unit. For example, a hydrocarbon molecule that is described as CH₃(CH₂)₅₀CH₃, is a molecule with fifty repeating units. If the number of repeating units is unknown or variable, the letter n may be used to indicate this formula: CH₃(CH₂)_nCH₃.

Ions

For ions, the charge on a particular atom may be denoted with a right-hand superscript. For example Na⁺, or Cu²⁺. The total charge on a charged molecule or a polyatomic ion may also be shown in this way. For example: H₃O⁺ or SO₄²⁻.

For more complex ions, brackets [ ] are often used to enclose the ionic formula, as in [B₁₂H₁₂]²⁻, which is found in compounds such as Cs₂[B₁₂H₁₂]. Parentheses ( ) can be nested inside brackets to indicate a repeating unit, as in [Co(NH₃)₆]³⁺. Here (NH₃)₆ indicates that the ion contains six NH₃ groups, and [ ] encloses the entire formula of the ion with charge +3.

Isotopes

Although isotopes are more relevant to nuclear chemistry or stable isotope chemistry than to conventional chemistry, different isotopes may be indicated with a prefixed superscript in a chemical formula. For example, the phosphate ion containing radioactive phosphorus-32 is ³²PO₄^3-. Also a study involving stable isotope ratios might include the molecule ¹⁸O¹⁶O.

A left-hand subscript is sometimes used redundantly to indicate the atomic number. For example, ₈O₂ for dioxygen, and ¹⁶₈O₂ for the most abundant isotopic species of dioxygen. This is convenient when writing equations for nuclear reactions, in order to show the balance of charge more clearly.

Empirical formulas

Main article: Empirical formula

In chemistry, the empirical formula of a chemical is a simple expression of the relative number of each type of atom or ratio of the elements in the compound. Empirical formulas are the standard for ionic compounds, such as CaCl₂, and for macromolecules, such as SiO₂. An empirical formula makes no reference to isomerism, structure, or absolute number of atoms. The term empirical refers to the process of elemental analysis, a technique of analytical chemistry used to determine the relative percent composition of a pure chemical substance by element.

For example hexane has a molecular formula of C₆H₁₄, or structurally CH₃CH₂CH₂CH₂CH₂CH₃, implying that it has a chain structure of 6 carbon atoms, and 14 hydrogen atoms. However, the empirical formula for hexane is C₃H₇. Likewise the empirical formula for hydrogen peroxide, H₂O₂, is simply HO expressing the 1:1 ratio of component elements. Formaldehyde and acetic acid have the same empirical formula, CH₂O. This is the actual chemical formula for formaldehyde, but acetic acid has double the number of atoms.

Trapped atoms

File:Endohedral fullerene.png

Traditional formula: MC₆₀
The "@" notation: M@C₆₀

Main article: Endohedral fullerene

The @ symbol (at sign) indicates an atom or molecule trapped inside a cage but not chemically bound to it. For example, a buckminsterfullerene (C₆₀) with an atom (M) would simply be represented as MC₆₀ regardless of whether M was inside the fullerene without chemical bonding or outside, bound to one of the carbon atoms. Using the @ symbol, this would be denoted M@C₆₀ if M was inside the carbon network. A non-fullerene example is [As@Ni₁₂As₂₀]^3-, an ion in which one As atom is trapped in a cage formed by the other 32 atoms.

This notation was proposed in 1991 with the discovery of fullerene cages (endohedral fullerenes), which can trap atoms such as La to form, for example, La@C₆₀ or La@C₈₂. The choice of the symbol has been explained by the authors as being concise, readily printed and transmitted electronically (the at sign is included in ASCII, which most modern character encoding schemes are based on), and the visual aspects suggesting the structure of an endohedral fullerene.

Non-stoichiometric formulas

Main article: Non-stoichiometric compound

Chemical formulas most often use integers for each element. However, there is a whole class of compounds, called non-stoichiometric compounds, that cannot be represented by small integers. Such a formula might be written using decimal fractions, as in Fe_0.95O, or it might include a variable part represented by a letter, as in Fe_1–xO, where x is normally much less than 1.

General forms for organic compounds

Chemical formula used for a series of compounds that differ from each other by a constant unit is called general formula. Such a series is called the homologous series, while its members are called homologs.
For example alcohols: C_nH_{(2n + 1)}OH (n ≥ 1)

Hill System

Main article: Hill system

The Hill system is a system of writing chemical formulas such that the number of carbon atoms in a molecule is indicated first, the number of hydrogen atoms next, and then the number of all other chemical elements subsequently, in alphabetical order. When the formula contains no carbon, all the elements, including hydrogen, are listed alphabetically. This deterministic system enables straightforward sorting and searching of compounds.

See also

• Empirical formula
• Structural formula
• Dictionary of chemical formulas
• Dictionary of chemical formulas/Merge
• Element symbol
• Nuclear notation
• Periodic table
• IUPAC nomenclature of inorganic chemistry

References

• ar:صيغة كيميائية